Ketamine Nasal Spray for Depression

Ann Arbor Counseling Associates
2 min readSep 15, 2023

What is Ketamine Nasal Spray?

Ketamine (esketamine), is an FDA approved anaesthetic available as a nasal spray that’s absorbed through the nasal lining and directly into your bloodstream. Ketamine Nasal Spray has been shown to relieve depression symptoms when combined with an oral antidepressant.

Ketamine Nasal Spray is designed to reduce the symptoms of:

  • Treatment-Resistant Depression (TRD)
  • TRD refers to patients whose depression has not improved despite taking at least two antidepressants.
  • About ⅓ of patients do not experience significant improvements with oral antidepressants.
  • Major Depressive Disorder (MDD) with suicidal thoughts or actions
  • Symptoms of Major Depressive Disorder (MDD) with suicidal thoughts or actions include:
  • Depresssed mood or feelings of sadness
  • Disrupted sleep
  • Lack of interest or inability to feel pleasure
  • Feelings of guilt or hopelessness
  • Lack of energy
  • Difficulty concentrating
  • Changes in appetite or weight
  • Slowed thoughts or movement
  • Restlessness and/or purposeless movement
  • Suicidal thoughts or actions

Is Ketamine Therapy right for me?

  • If you haven’t seen any improvements in your depression after trying at least two different antidepressants.
  • Schedule an evaluation with us to see if Ketamine Therapy may benefit you. We will review your family and medical history, as well as your previous medications, to determine whether Ketamine Nasal Spray is the right medication for you.

Your Path to Treatment with Ketamine Therapy

  • Your first appointment will be a Ketamine Therapy Assessment with a clinician and a follow-up evaluation appointment by our prescriber. Evaluation based on family and medical history is necessary to determine whether SPRAVATO® is right for you.
  • Prior to meeting with a clinician, you will be asked to complete forms and paperwork.
  • At that time your insurance benefits will be verified to confirm the cost of Ketamine Nasal Spray for you.

Find out if you’re eligible for Ketamine Therapy for Major Depression, Click here.

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